Taking advantage of the first annual reports, SPHN Projects were requested to provide information on infrastructure built in 2018 in a structured way, determining the research orientation of their project as well as degree of implementation. In 2019, this information was used to create a first mapping and to start a gap analysis.
The mapping shows that many domains are covered by the projects, however, it seems that more activities in the “patient or citizen oriented” and “national repositories, technology and analytical networks” domains might be needed. Explore the diagram and hover over the project abbreviations to display the full name of the project.
Development of a governance and quality management system for exchange of patient related data for research purposes
Development and Implementation of a Nationwide Harmonized Interactive Electronic General Consent
De-identification of clinical narrative data in French, German and Italian
Swiss Variant Interpretation Platform for Oncology
Harmonising the collection of health-related data and biospecimens in paediatric hospitals throughout Switzerland
Citizen Centered Consent: Shared, Transparent and Dynamic
NLP-powered mapping of clinical reports onto SNOMED-CT concepts for tumour classification
LOINC for Swiss Laboratories
Swiss Ophthalmic Imaging Network
The Swiss Ageing Citizen Reference
SWISSHEART Failure Network
Clinical Research from multi-modality big data sources without proprietary interfaces in a multicenter approach
Radiomics for comprehensive patient and disease phenotyping in personalized health
Swiss Personalized Oncology
Swiss Frailty Network and Repository
Personalized Swiss Sepsis Study: Detection and modelling of sepsis using machine learning to analyse continuous ICU monitoring, laboratory, microbiology, and -omics data for personalized sepsis management
Identification of biomarkers and therapeutic targets in inflammatory disease immunotherapy by high-dimensional single cell analysis and cluster proteomics
Population-wide screens of the human immune repertoire: a reverse personalized-medicine approach
Swiss Molecular Pathology Breakthrough Platform
Optimising paediatric dosing regimens based on a clinical data warehouse
Quality Assessment for Interoperable Quantitative CT-Imaging
A platform for clinical grade interpretation of genetic variants to foster personalized health care in Switzerland
Personalized reference values for precision medicine
Enabling the Secure and Privacy-Preselving Exploration of Distributed Clinical and *Omics Cohorts in the SPHN
* projects co-funded by SPHN and PHRT.
Source: Annual activity reports of the projects.
24 SPHN Driver and Infrastructure Development Projects:
35 Swiss organizations and Institutions contributing to the research.
13 Infrastructure Development Projects:
Developing and testing new technologies, methods and infrastructures at single or joint sites, to be made available to other institutions after proof of concept (CHF 3.7 million).
11 Driver Projects:
Guiding the development of SPHN by “test driving” the infrastructures and interoperability for multi-site research in a specific area or pathology. Each driver project typically involves multiple “data providers” (predominantly University Hospitals, but also Universities and analytic platforms) as well as teams of “data recipients” who analyze the data, which is securely transferred from the “data providers” to the “data recipients” via the BioMedIT network (CHF 21.6 million).
Click on the project acronym on the left-hand side to display the collaborations of each individual project. To access the project lay summaries, click on the full project name, appearing above the illustration.
SIB Swiss Institute of Bioinformatics
Universitäts-Kinderspital beider Basel
Hôpitaux Universitaires Genève
Centre hospitalier universitaire vaudois
Swiss Tropical and Public Health Institute
Univérsité de Lausanne
École polytechnique fédérale de Lausanne
Haute Ecole Spécialisée de Suisse occidentale
Université de Genève
Paul Scherrer Institut
Eidgenössische Technische Hochschule Zürich
Istituto cantonale di patologia
Schweizer Paraplegiker Zentrum
Swiss Research Network of Clinical Pediatric Hubs
Swiss Biobanking Plattform
Swiss Clinical Trial Organisation
Centre universitaire de médecine générale et santé publique
Swiss Group for Clinical Cancer Research (SAKK)
Kantonsspital St. Gallen
Hôpital du Valais
Klinik für Kinder und Jugendliche, Kantonsspital Aarau
Ente Ospedaliero Cantonale
Universitäre Altersmedizin FELIX PLATTER
Source: Projects' layman summaries and PI feedback from November 2019.