The SPHN Management Office (MO) together with the SIB Personalized Health Informatics Group ((PHI) coordinate the funding and drive the development of coordinated infrastructures, compatible data management systems, interoperability of data and governance of guidelines.

While the MO is in charge of the administrative and the daily operation of the  SPHN initiative, the PHI Group is in charge of the SPHN Data Coordination Center (DCC) and the BioMedIT network project, a national IT infrastructure backbone, to enable nationwide health-data exchange for research. BioMedIT provides researchers all over Switzerland with access to a secure and protected computing environment for analysis of sensitive data without compromising data privacy. National, scalable and sustainable.

Key in the pioneering implementation and coordination of the national infrastructure is the voluntary contribution of the SPHN Expert Advisory Groups and the SPHN Data Coordination Center (DCC) Working Groups.

Members of these advisory- and working groups are all national and international experts in a key focus area, such as clinical and molecular medicine, semantics, bioinformatics, technolomics, information technology, IT security and interoperability, data science, ethics and law.