Within the Swiss Personalized Health Network and related national initiatives, researchers use patient data (i.e. confidential human data) in their research projects. Dealing with confidential human data requires awareness of data privacy, respective laws and information security. The SPHN training on Data Privacy and IT Security explains what should be done in practice to protect the patients’ privacy when performing biomedical research on human data. For researchers and users of the SPHN/BioMedIT infrastructure this course is highly recommended. The respective exam is mandatory to use the BioMedIT infrastructure.